49ers vs. Seahawks NFL DFS: Best DraftKings, FanDuel daily Fantasy football picks for Thursday Night Football


The 49ers are hoping to get Deebo Samuel (ankle) before the playoffs, but they can’t get a versatile player for Thursday night’s game against the Seahawks. Few players can replace Samuel’s production in the NFL DFS lineup, but San Francisco has other heavyweights to count on, including Christian McCaffrey and George Kittle. What other Niners receivers could influence NFL DFS picks and influence everyday fantasy football strategy? Jauan Jennings and Ray-Ray McCloud take more snaps against Brandon Aiyuk I play it, but neither are elements of a run game like Samuel. Which lesser-known option could be a low-cost, high-paying NFL DFS sleeper in 49ers vs. Seahawks Before picking his NFL DFS in 49ers vs. Seahawks on Thursday Night Football. Check out NFL DFS advice and strategies from SportsLine Daily Fantasy Expert Mike McClure.

McClure is a legendary professional DFS player who has earned over $2 million in prize money in his career. His methodology has brought in huge amounts of cash with FanDuel and DraftKings. In his 2020 at FanDuel he won two high stakes tournaments and at DraftKings he recorded two top 10 finishes in tournaments with over 130,000 participants. His lineup has also finished within the top 1% of his other 12+ tournaments.

He uses powerful predictive models to simulate every snap of NFL action, factoring in factors like matchups, statistical trends and injuries. This allows him to find the optimal value for his DFS, which he shares only with members of SportsLine.

This year he has already won the DraftKings Millionaire Maker twice and the FanDuel Million once. Now, McClure has his sights set on his NFL DFS game of the 49ers vs. Seahawks, and daily fantasy picks his top football picks. His picks and analysis can be found exclusively on SportsLine.

Seahawks vs. 49ers’ top NFL DFS picks

One of McClure’s top picks in the NFL DFS on Thursday Night Football is 49ers running back Christian McCaffrey. The versatile back showcased his three-down ability last week as he tallied 119 yards on the ground and he scored one and added another 34 yards for an aerial touchdown. In the past six games, McCaffrey’s 24.6 fantasy points per game ranks him second in the NFL among non-quarterbacks.

Seattle ranked 31st in run defense and conceded the second-most fantasy points to opposing running backs. One of McCaffrey’s best assets is his ability to catch passes from the backfield. Slightly he allowed a running back two teams more receiving yards than Seattle, so that should show perfectly in his TNF.

Part of McClure’s optimal NFL DFS strategy also includes signing 49ers quarterback Brock Purdy. Jimmy Garoppolo has avoided Lisfranc surgery but is still out for the rest of the regular season. The 7th round pick has been acquitted since his inauguration. Purdy had an interception in a Garoppolo relief two weeks ago against Miami for 210 yards and two touchdowns as he went 25-for-37 and had an even more efficient outing in Week 14. I was.

The 49ers defended him in a dynamic run game, but Purdy did a good job whenever called up, completing 16 of 21 passes for 185 yards and two touchdowns, and a rushing score. The Iowa product was accurate when requested and still has a strong supporting cast featuring Christian McCaffrey, George Kittle and Brandon Ayuk. McClure’s TNF DFS Advice The rest can be found here.

How to Build an NFL DFS Lineup for Thursday Night Football

McClure also targets another underrated player who could be a big blast in Thursday Night Football. This pick could be the difference between tournaments and cash he wins games or goes home with nothing. Who that is, and the rest of McClure’s NFL DFS picks, can only be found on SportsLine.

Who does Mike McClure include in the best NFL DFS lineup for the Seahawks vs. 49ers? And who are the players to watch out for? Check out and find the best NFL DFS picks, leaderboards, advice and stacks from DFS experts who have won over a dollar.


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